SCHEMBL28830488

SCHEMBL28830488

OCCC[C@@H](CO)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.41
GSR P00390 1/20 0.39
HRH1 P35367 4/20 0.39
HTR2A P28223 3/20 0.39
GABBR2 O75899 2/20 0.38
GABBR1 Q9UBS5 2/20 0.38
HDAC3 O15379 3/20 0.37
HDAC4 P56524 3/20 0.37
HDAC1 Q13547 3/20 0.37
HDAC7 Q8WUI4 3/20 0.37
HDAC2 Q92769 3/20 0.37
HDAC10 Q969S8 3/20 0.37
HDAC11 Q96DB2 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
HDAC6 Q9UBN7 3/20 0.37
HDAC9 Q9UKV0 3/20 0.37
HDAC5 Q9UQL6 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28830491 1.00 TRPA1 (0.41) TRPA1ALDH1A1LMNAHSD17B10GSR
SCHEMBL6520180 0.91 TRPA1 (0.44) TRPA1ALDH1A1LMNAHSD17B10GSR
SCHEMBL19094051 0.87 TRPA1 (0.46) TRPA1ALDH1A1LMNAHSD17B10GSR
SCHEMBL1507699 0.86 TRPA1 (0.48) TRPA1ALDH1A1LMNAGSRHRH1
SCHEMBL1546696 0.86 TRPA1 (0.48) TRPA1ALDH1A1LMNAGSRHRH1
SCHEMBL8274952 0.86 TRPA1 (0.48) TRPA1ALDH1A1LMNAGSRHRH1
SCHEMBL18098106 0.85 TRPA1 (0.44) TRPA1ALDH1A1LMNAHSD17B10GSR
SCHEMBL1144368 0.83 LMNA (0.47) TRPA1ALDH1A1LMNAHSD17B10HRH1
SCHEMBL22808422 0.83 POLB (0.46) TRPA1ALDH1A1LMNA
SCHEMBL821043 0.83 POLB (0.46) TRPA1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957304-B Chiral 1, 5-diborane compound and synthetic method and application thereof 浙江大学 2024-06-21 CN disclosed
CN-114957304-A Chiral 1, 5-diborane compound and synthesis method and application thereof 浙江大学 2022-08-30 CN disclosed