SCHEMBL28830561

SCHEMBL28830561

OCCC[C@@H](CO)c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
CYP2C19 P33261 4/20 0.44
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 3/20 0.44
KDM4E B2RXH2 2/20 0.42
HPGD P15428 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
SLC6A4 P31645 1/20 0.40
ACP3 P15309 3/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HTT P42858 1/20 0.38
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692988 0.89 CYP2C19 (0.47) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL7385565 0.87 ALDH1A1 (0.42) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL7381122 0.87 ALDH1A1 (0.42) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL9352587 0.85 CYP2C19 (0.54) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL8957571 0.84 KMT2A (0.45) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL7384532 0.83 ALDH1A1 (0.44) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL10568604 0.81 HTR1B (0.47) ALDH1A1CYP2C19CYP1A2CYP2C9SLC6A4
Hydrochloric Acid SCHEMBL9631831 0.79 HTR1B (0.46) ALDH1A1CYP2C19CYP1A2CYP2C9SLC6A4
SCHEMBL6301621 0.79 ALDH1A1 (0.44) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E
SCHEMBL467398 0.79 ALDH1A1 (0.41) ALDH1A1CYP2C19CYP1A2CYP2C9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957304-B Chiral 1, 5-diborane compound and synthetic method and application thereof 浙江大学 2024-06-21 CN disclosed
CN-114957304-A Chiral 1, 5-diborane compound and synthesis method and application thereof 浙江大学 2022-08-30 CN disclosed