Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 12/20 | 0.69 |
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.69 |
| ▸ | PARP1 | P09874 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | GUSB | P08236 | 6/20 | 0.60 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.82 | TNKS (0.93) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL29592833 | 0.82 | TNKS (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL258433 | 0.82 | TNKS (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL31529601 | 0.80 | TNKS (0.96) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL6695759 | 0.80 | TNKS2 (0.81) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL3460177 | 0.80 | HPGD (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL29831923 | 0.80 | HPGD (1.00) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL6124189 | 0.79 | TNKS (0.93) | TNKSTNKS2PARP1HPGDMAPT | |
| SCHEMBL9030999 | 0.78 | NPC1 (0.62) | HPGDMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8620410 | 0.78 | TNKS (0.83) | TNKSTNKS2PARP1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |