Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135 | 0.96 | — | — | |
| SCHEMBL8579517 | 0.96 | LMNA (0.52) | LMNAMAPTCYP2A6KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5903833 | 0.93 | — | — | |
| Bromide SCHEMBL1446624 | 0.93 | — | — | |
| SCHEMBL31446808 | 0.93 | — | — | |
| Methane SCHEMBL28514675 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL146858 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL27625573 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL28832512 | 0.90 | — | — | |
| Bromide SCHEMBL27577669 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010656-B | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-115010656-A | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-115010656-B | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115010656-B | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115010656-A | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-115010656-A | Preparation method of 5-acetyl-2-bromopyridine | 苏州昊帆生物股份有限公司 | 2022-09-06 | — | — | CN | disclosed |