SCHEMBL28831007

SCHEMBL28831007

N[C@@H]1CN(c2ccc(Br)cc2)C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.41
FAAH O00519 1/20 0.39
MGLL Q99685 1/20 0.39
MAPT P10636 2/20 0.37
ROCK2 O75116 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HSP90AA1 P07900 1/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 3/20 0.36
CYP2C9 P11712 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28831010 1.00 RXFP1 (0.41) RXFP1FAAHMGLLMAPTROCK2
SCHEMBL18048600 0.81 ROCK2 (0.47) RXFP1FAAHMGLLMAPTROCK2
SCHEMBL29187460 0.81 ALOX15 (0.45) MGLLMAPTHSP90AA1POLBMEN1
SCHEMBL30777491 0.81 TP53 (0.47) MGLLMEN1KMT2ATSHRMAPK1
SCHEMBL29187457 0.81 ALOX15 (0.45) MGLLMAPTHSP90AA1POLBMEN1
SCHEMBL13818358 0.80 MEN1 (0.48) MAPTPOLBMEN1KMT2ATSHR
SCHEMBL20555476 0.79 ROCK2 (0.42) RXFP1FAAHMGLLROCK2HSP90AA1
SCHEMBL20555551 0.79 ROCK2 (0.42) RXFP1FAAHMGLLROCK2HSP90AA1
SCHEMBL4683505 0.79 ROCK2 (0.42) RXFP1FAAHMGLLROCK2HSP90AA1
Hydrochloric Acid SCHEMBL20555840 0.78 ROCK2 (0.41) RXFP1FAAHMGLLROCK2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957385-B Dipeptide compound containing beta-lactam ring, preparation method and application thereof 浙大城市学院 2024-02-27 CN disclosed
CN-114957385-A Dipeptide compound containing beta-lactam ring, preparation method and application thereof 浙大城市学院 2022-08-30 CN disclosed