SCHEMBL28831705

SCHEMBL28831705

O=C(ON=C(CC1CCCC1)C(=O)c1ccc(SCc2ccccc2)cc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HAO1 Q9UJM8 1/20 0.38
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPT P10636 3/20 0.37
PPARG P37231 2/20 0.36
PPARA Q07869 1/20 0.36
KDM4E B2RXH2 1/20 0.36
EPHX2 P34913 1/20 0.35
POLB P06746 2/20 0.35
PKM P14618 2/20 0.34
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15960798 0.87 POLB (0.37) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL17070002 0.87 POLB (0.37) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL17644162 0.87 POLB (0.37) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL17069998 0.86 POLB (0.39) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL17540445 0.86 POLB (0.39) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL31621087 0.86 POLB (0.39) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28512154 0.83 SMN1; SMN2 (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL17540446 0.82 NPC1 (0.39) NPC1RAB9ASMN1; SMN2ALDH1A1HPGD
SCHEMBL28831707 0.82 HAO1 (0.43) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL28408599 0.80 HPGD (0.39) NPC1RAB9ASMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114967338-A Green photosensitive resin composition, color filter and display device manufactured by using same 东友精细化工有限公司 2022-08-30 CN disclosed