SCHEMBL28831708

SCHEMBL28831708

O=Cc1ccc(-c2ccc(C(=C(c3ccccc3)c3ccccc3)c3ccccc3)cc2)s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.59
CYP2E1 P05181 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2A6 P11509 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2B6 P20813 1/20 0.49
CYP2C19 P33261 1/20 0.49
NQO2 P16083 2/20 0.44
DPP4 P27487 1/20 0.44
PRF1 P14222 1/20 0.43
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
RAB9A P51151 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PTPN1 P18031 1/20 0.40
PTPN11 Q06124 1/20 0.40
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28831656 0.97 APP (0.64) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL28515376 0.89 APP (0.49) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL7905308 0.84 APP (0.68) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL70783 0.84 APP (0.67) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL2015912 0.83 APP (0.54) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL20420082 0.82 NQO2 (0.60) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL10472980 0.80 APP (0.73) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL2015377 0.78 PRF1 (0.56) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL2016057 0.78 PRF1 (0.56) APPCYP2E1CYP3A4CYP2A6CYP2C9
SCHEMBL2557368 0.78 HDAC1 (0.57) APPCYP2E1CYP3A4CYP2A6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146208-A Fluorescent probe for detecting hydrogen sulfide in plants and preparation method and application thereof 河南农业大学 2024-06-07 CN claimed
CN-118146208-A Fluorescent probe for detecting hydrogen sulfide in plants and preparation method and application thereof 河南农业大学 2024-06-07 CN disclosed
CN-118005601-A Compound with aggregation-induced emission performance and preparation method thereof 五邑大学 2024-05-10 CN disclosed
CN-114989189-B Compound with aggregation-induced emission performance, and preparation method and application thereof 西南交通大学 2023-09-26 CN disclosed
CN-114989189-A Compound with aggregation-induced emission performance and preparation method and application thereof 西南交通大学 2022-09-02 CN disclosed