SCHEMBL28831920

SCHEMBL28831920

CC(N)(N)CCNC1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.42
KDM4E B2RXH2 4/20 0.38
CXCR4 P61073 6/20 0.37
CXCL12 P48061 1/20 0.37
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C19 P33261 2/20 0.35
LMNA P02545 1/20 0.35
ANPEP P15144 2/20 0.34
ERAP2 Q6P179 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28831909 0.98 RAD52 (0.39) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL3645463 0.83 RAD52 (0.44) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL13912964 0.80 RAD52 (0.41) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL25087694 0.79 KDM4E (0.42) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL16371125 0.76 KDM4E (0.40) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL12156771 0.76 RAD52 (0.37) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL21088960 0.76 GNAI3 (0.34) LMNA
SCHEMBL2632339 0.75 CXCR4 (0.44) RAD52KDM4ECXCR4CXCL12LMNA
SCHEMBL6059264 0.75 RAD52 (0.39) RAD52KDM4ECXCR4CXCL12CYP1A2
SCHEMBL9349514 0.75 RAD52 (0.39) RAD52KDM4ECXCR4CXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853633-A Preparation method of bisaminopropyl alicyclic tertiary amine 万华化学集团股份有限公司 2022-08-05 CN claimed
CN-114853633-A Preparation method of bisaminopropyl alicyclic tertiary amine 万华化学集团股份有限公司 2022-08-05 CN disclosed