Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803995 | 0.80 | GNAI3 (0.36) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL28831909 | 0.77 | RAD52 (0.39) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL477233 | 0.77 | FABP6 (0.44) | ALDH1A1LMNA | |
| SCHEMBL21799523 | 0.76 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 | |
| SCHEMBL28831920 | 0.76 | RAD52 (0.42) | LMNA | |
| SCHEMBL12477911 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7296519 | 0.74 | ALDH1A1 (0.39) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL16817812 | 0.74 | GAA (0.41) | MEN1ALDH1A1LMNAGAAALOX12 | |
| SCHEMBL12391785 | 0.71 | GNAI3 (0.42) | GNAI3GNAO1GNAI1MEN1ALDH1A1 | |
| SCHEMBL12156771 | 0.71 | RAD52 (0.37) | GNAI3GNAO1GNAI1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |