Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 16/20 | 0.43 |
| ▸ | IDH2 | P48735 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085661 | 0.83 | IDH1 (0.51) | IDH1IDH2CTSK | |
| SCHEMBL26618081 | 0.81 | IDH1 (0.42) | IDH1IDH2CTSK | |
| SCHEMBL22547299 | 0.75 | CTSK (0.42) | CTSK | |
| SCHEMBL17700614 | 0.74 | GRM4 (0.45) | IDH1IDH2 | |
| SCHEMBL26618136 | 0.73 | GRM4 (0.39) | IDH1IDH2 | |
| SCHEMBL15710124 | 0.70 | IDH1 (0.36) | IDH1IDH2 | |
| SCHEMBL21525591 | 0.70 | HPGD (0.45) | CTSK | |
| SCHEMBL26618090 | 0.70 | NOS2 (0.36) | IDH1IDH2 | |
| SCHEMBL24065676 | 0.69 | IDH1 (0.44) | IDH1IDH2 | |
| SCHEMBL22547655 | 0.68 | CTSK (0.34) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947305-B | Compounds and methods for kinase modulation and indications therefor | 普莱希科公司 | 2016-07-06 | — | — | CN | claimed |
| CN-102947305-B | Compounds and methods for kinase modulation and indications therefor | 普莱希科公司 | 2016-07-06 | — | — | CN | disclosed |