Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448049 | 0.89 | ADRA2A (0.41) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL27279321 | 0.81 | EGLN1 (0.43) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL3455393 | 0.81 | CYP1A2 (0.47) | TSHRNR1I2PGRADORA3PTGS2 | |
| SCHEMBL6552702 | 0.80 | TSHR (0.52) | TSHRMAPTNR1I2PGRADORA3 | |
| SCHEMBL6550916 | 0.80 | TSHR (0.52) | TSHRMAPTNR1I2PGRADORA3 | |
| SCHEMBL27450682 | 0.80 | TSHR (0.52) | TSHRMAPTNR1I2PGRADORA3 | |
| SCHEMBL27331787 | 0.80 | TSHR (0.47) | TSHRADRA2AADRA1AMAPTNR1I2 | |
| SCHEMBL9911957 | 0.80 | KDM4E (0.52) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL28177202 | 0.79 | TSHR (0.35) | TSHRADRA2AADRA1AMAPTBLM | |
| SCHEMBL6552434 | 0.78 | TSHR (0.55) | TSHRMAPTNR1I2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104145010-B | Lubricating oil composition | 出光兴产株式会社 | 2016-08-31 | — | — | CN | disclosed |