Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189182 | 0.98 | TSHR (0.45) | TSHRHSP90B1LMNAPPM1BPTPN1 | |
| SCHEMBL2189191 | 0.98 | TSHR (0.45) | TSHRHSP90B1LMNAPPM1BPTPN1 | |
| SCHEMBL29981924 | 0.96 | TSHR (0.46) | TSHRHSP90B1LMNAPPM1BPTPN1 | |
| SCHEMBL6666772 | 0.84 | PPM1B (0.41) | TSHRHSP90B1PPM1BPTPN1PPP1CC | |
| SCHEMBL28475631 | 0.81 | LGALS3 (0.33) | — | |
| SCHEMBL27766467 | 0.81 | AHCY (0.45) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL14317077 | 0.81 | AHCY (0.45) | TSHRLMNAPPM1BPTPN1PPP1CC | |
| SCHEMBL27737603 | 0.80 | LGALS3 (0.46) | TSHRHSP90B1LMNAPPM1BPTPN1 | |
| SCHEMBL28214269 | 0.79 | AHCY (0.34) | HSP90B1 | |
| SCHEMBL19226382 | 0.79 | TSHR (0.41) | TSHRHSP90B1PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029106-A | Coagulation factor IX conjugates | 诺和诺德保健股份有限公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105979972-A | Factor viii conjugates | 诺和诺德股份有限公司 | 2016-09-28 | — | — | CN | disclosed |