Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28092562 | 0.87 | AVPR1A (0.49) | HSD11B1AVPR1AKMT2AALDH1A1GAA | |
| SCHEMBL28833120 | 0.80 | AVPR1A (0.51) | HSD11B1AVPR1AKMT2AALDH1A1MAPT | |
| SCHEMBL28092466 | 0.80 | BCHE (0.48) | HSD11B1AVPR1AGPBAR1 | |
| SCHEMBL28092460 | 0.80 | AVPR1A (0.45) | HSD11B1AVPR1AKMT2AALOX15ALDH1A1 | |
| SCHEMBL28092473 | 0.79 | BCHE (0.51) | HSD11B1AVPR1AALDH1A1KDM4EGPBAR1 | |
| SCHEMBL28092698 | 0.79 | BCHE (0.51) | HSD11B1AVPR1AKMT2AALDH1A1MAPT | |
| SCHEMBL28092682 | 0.79 | AVPR1A (0.43) | HSD11B1AVPR1AALOX15ALDH1A1GPR6 | |
| SCHEMBL28092668 | 0.77 | MGLL (0.51) | AVPR1AALDH1A1 | |
| SCHEMBL28092670 | 0.76 | TRPV1 (0.46) | AVPR1AKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28092729 | 0.76 | MGLL (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-A | Benzopiperazine compositions as BET bromodomain inhibitors | 福马疗法公司 | 2016-10-12 | — | — | CN | disclosed |