Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28092466 | 0.89 | BCHE (0.48) | AVPR1AHSD11B1BCHEGPBAR1 | |
| SCHEMBL28833120 | 0.89 | AVPR1A (0.51) | AVPR1AHSD11B1BCHEALDH1A1GPBAR1 | |
| SCHEMBL28092460 | 0.89 | AVPR1A (0.45) | AVPR1AGAAHSD11B1ALDH1A1GPBAR1 | |
| SCHEMBL28833101 | 0.87 | HSD11B1 (0.44) | AVPR1AGAAHSD11B1ALDH1A1GPBAR1 | |
| SCHEMBL28092698 | 0.86 | BCHE (0.51) | AVPR1AHSD11B1BCHEALDH1A1GPBAR1 | |
| SCHEMBL28092473 | 0.86 | BCHE (0.51) | AVPR1AHSD11B1BCHEALDH1A1GPBAR1 | |
| SCHEMBL28092682 | 0.86 | AVPR1A (0.43) | AVPR1AGAAHSD11B1ALDH1A1GPBAR1 | |
| SCHEMBL28092729 | 0.85 | MGLL (0.48) | ALDH1A1SMN1; SMN2MGLL | |
| SCHEMBL28092668 | 0.84 | MGLL (0.51) | AVPR1AALDH1A1MGLLCYP3A4TSHR | |
| SCHEMBL28092670 | 0.83 | TRPV1 (0.46) | AVPR1AGAAALDH1A1GPBAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029076-A | Benzopiperazine compositions as BET bromodomain inhibitors | 福马疗法公司 | 2016-10-12 | — | — | CN | disclosed |