Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826540 | 0.80 | ALDH1A1 (0.44) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL29736537 | 0.80 | ALDH1A1 (0.44) | MAPTMEN1KMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL9696874 | 0.76 | MAPK1 (0.47) | MAPTMEN1KMT2ANPC1LMNA | |
| SCHEMBL3500189 | 0.75 | MAP4K4 (0.49) | MAP4K4MAPTCNR1MAPKAPK2BACE1 | |
| SCHEMBL30269925 | 0.73 | RAB9A (0.49) | MEN1RAB9AALDH1A1PDE4D | |
| SCHEMBL28365402 | 0.73 | RAB9A (0.49) | MEN1RAB9AALDH1A1PDE4D | |
| SCHEMBL16242324 | 0.71 | MAP4K4 (0.62) | MAP4K4MAPTMEN1KMT2ACNR1 | |
| SCHEMBL11623808 | 0.71 | STAT3 (0.46) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28720537 | 0.70 | TSHR (0.48) | MAPTLMNAALDH1A1TDP1TSHR | |
| SCHEMBL21952859 | 0.69 | SCN9A (0.38) | MAPTRAB9ANPC1ALDH1A1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849097-A | Substituted pyridine derivatives as GSK-3 inhibitors | 百时美施贵宝公司 | 2016-08-10 | — | — | CN | disclosed |