SCHEMBL28833138

SCHEMBL28833138

C=C(C)C(=O)OSc1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
MAPT P10636 8/20 0.38
ALDH1A1 P00352 7/20 0.38
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38
HPGD P15428 4/20 0.38
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ELANE P08246 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DNMT1 P26358 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2780454 0.87 HPGD (0.45) LMNAMAPTALDH1A1KMT2AHTT
SCHEMBL27855539 0.87 ALDH1A1 (0.37) LMNAMAPTALDH1A1KMT2AHTT
SCHEMBL27890648 0.84 ALDH1A1 (0.34) LMNAMAPTALDH1A1KMT2AHPGD
SCHEMBL28093205 0.84 MAPT (0.40) LMNAMAPTALDH1A1HTTHPGD
SCHEMBL27535831 0.83 ELANE (0.45) LMNAMAPTALDH1A1HTTHPGD
SCHEMBL21332455 0.80 LMNA (0.48) LMNAMAPTALDH1A1KMT2AHTT
SCHEMBL28055289 0.80 ALDH1A1 (0.34) MAPTALDH1A1KMT2AELANE
SCHEMBL26303217 0.77 CA1 (0.45) LMNAMAPTALDH1A1HTTHPGD
SCHEMBL13652110 0.76 ALDH1A1 (0.43) LMNAMAPTALDH1A1KMT2AHTT
SCHEMBL20628311 0.76 GAA (0.43) MAPTALDH1A1KMT2AHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103890018-B Polyfunctional (meth) acrylate having fluorene skeleton and curable composition thereof 大阪燃气化学有限公司 2016-08-17 CN disclosed