Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29886939 | 1.00 | FFAR1 (0.40) | FFAR1ARXDHESRRATRPV4 | |
| SCHEMBL1303864 | 0.88 | ALDH1A1 (0.40) | FFAR1ARESRRATRPV4MAPT | |
| SCHEMBL22323924 | 0.87 | TRPV4 (0.40) | FFAR1ARXDHTRPV4MAPT | |
| SCHEMBL5089148 | 0.85 | TRPV4 (0.42) | FFAR1ARESRRATRPV4MAPT | |
| SCHEMBL15170403 | 0.84 | AR (0.45) | ARXDHTRPV4MAPTPTGDR2 | |
| SCHEMBL944720 | 0.83 | TRPV4 (0.53) | FFAR1ARTRPV4MAPTL3MBTL1 | |
| SCHEMBL1303515 | 0.82 | FFAR1 (0.38) | FFAR1ARESRRATRPV4MAPT | |
| SCHEMBL31151408 | 0.81 | MRGPRX4 (0.49) | ARXDHESRRATRPV4ALDH1A1 | |
| SCHEMBL1734101 | 0.81 | AR (0.54) | ARXDHTRPV4MAPTLMNA | |
| SCHEMBL30118209 | 0.80 | AR (0.51) | FFAR1ARESRRAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981251-B | Dibenzofuran derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114981251-A | Diphenyl furan derivative cathepsin K inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |