SCHEMBL2883348

SCHEMBL2883348

[CH2]CCCCCCOC([O])=O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 1/20 0.44
NAAA Q02083 1/20 0.37
EPHX1 P07099 1/20 0.34
ACHE P22303 6/20 0.33
LMNA P02545 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
RAD52 P43351 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930309 1.00 TSHR (0.44) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL2884406 0.97
SCHEMBL2888949 0.90
SCHEMBL23093044 0.82 TSHR (0.46) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL11169493 0.81 TSHR (0.44) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL129583 0.80 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL7841371 0.80 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL5397748 0.80 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL9357943 0.80 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4NAAAEPHX1
SCHEMBL2688058 0.80 ALDH1A1 (0.58) TSHRALDH1A1CYP3A4NAAAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8568839-B2 Liquid crystal composition and retardation film FUJIFILM CORPORATION (JP) 2013-10-29 US disclosed
US-8257611-B2 Optical film and retardation sheet, and liquid crystal compound FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-7811469-B2 Vertical alignment film and VA mode liquid crystal cell FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20100078593-A1 LIQUID CRYSTAL COMPOSITION AND RETARDATION FILM FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100045901-A1 OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-7645496-B2 1,3,5-triazine compound, composition, and optically anisotropic material composed of the same FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20090268143-A1 VERTICAL ALIGNMENT FILM AND VA MODE LIQUID CRYSTAL CELL FUJIFILM CORPORATION (JP) 2009-10-29 US disclosed
US-20090213462-A1 OPTICAL FILM, POLARIZATION PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-08-27 US disclosed
US-7575696-B2 Liquid crystal composition and anisotropic material FUJIFILM CORPORATION (JP) 2009-08-18 US disclosed
US-20090189120-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND ANISOTROPIC MATERIAL FUJIFILM CORPORATION (JP) 2009-07-30 US disclosed
WO-2008072794-A1 OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND FUJIFILM CORPORATION (JP) 2008-06-19 WO disclosed
US-20080023670-A1 LIQUID CRYSTAL COMPOSITION AND ANISOTROPIC MATERIAL FUJIFILM CORPORATION (JP) 2008-01-31 US disclosed
US-20070298192-A1 1,3,5-Triazine compound, composition, and optically anisotropic material composed of the same FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090189120-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION, AND ANISOTROPIC MATERIAL CCNA2, CCNA1, CCNB2 TSHR 3557/4885ALDH1A1 2881/4885CYP3A4 2602/4885
US-20100045901-A1 OPTICAL FILM AND RETARDATION SHEET, AND LIQUID CRYSTAL COMPOUND C1R, CCNA1, C5 TSHR 729/4885ALDH1A1 3648/4885CYP3A4 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.