Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297163 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL9357943 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL4740813 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL9362486 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL10887363 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL7841371 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL2688058 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL5397748 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR | |
| SCHEMBL133539 | 0.97 | — | — | |
| SCHEMBL9193886 | 0.92 | ALDH1A1 (0.61) | ALDH1A1LMNAAPOBEC3AAPOBEC3GTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | claimed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | claimed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | claimed |
| EP-3162799-A1 | FLUOROALKYLATING AGENT | Ihara Chemical Industry Co., Ltd. (JP) | 2017-05-03 | — | — | EP | claimed |
| EP-1047431-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF | TUFTS COLLEGE (US) | 2012-12-12 | — | — | EP | claimed |
| EP-1558654-A4 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | FUJIFILM ELECTRONIC MATERIALS (US) | 2006-04-05 | — | — | EP | claimed |
| US-20050250744-A1 | Pharmaceutically active compounds and methods of use thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2005-11-10 | — | — | US | claimed |
| EP-1558654-A2 | NOVEL COPOLYMER, PHOTORESIST COMPOSITIONS THEREOF AND DEEP UV BILAYER SYSTEM THEREOF | Fujifilm Electronic Materials USA, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| US-6916543-B2 | Copolymer, photoresist compositions thereof and deep UV bilayer system thereof | ARCH SPECIALTY CHEMICALS, INC. (US) | 2005-07-12 | — | — | US | claimed |
| EP-1047431-A4 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF | TUFTS COLLEGE (US) | 2004-12-08 | — | — | EP | claimed |
| US-20020123637-A1 | 5,9-substituted tetracycline; antibacterial activity, including against both gram-positive and gram-negative bacteria | TRUSTEES OF TUFTS COLLEGE | 2002-09-05 | — | — | US | claimed |
| EP-1047431-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2000-11-02 | — | — | EP | claimed |
| WO-1999037306-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 1999-07-29 | — | — | WO | claimed |
| WO-1999037307-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 1999-07-29 | — | — | WO | claimed |
| EP-0323757-B1 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES (JP) | 1995-05-10 | — | — | EP | claimed |
| EP-0297710-B1 | DISPERSE DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-02 | — | — | EP | claimed |
| US-4931455-A | Alkylaminopyrimidine derivative and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1990-06-05 | — | — | US | claimed |
| US-4881943-A | Disperse dyes: nitro-thiophene azo dyes for bright blue shades on polyester | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-11-21 | — | — | US | claimed |
| EP-0323757-A2 | Alkylaminopyrimidine derivative, process for producing the same, and insecticide, acaricide and fungicide containing the same as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1989-07-12 | — | — | EP | claimed |
| EP-0297710-A1 | Disperse dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020123637-A1 | 5,9-substituted tetracycline; antibacterial activity, including against both gram-positive and gram-negative bacteria | TLR5, HDAC5, TET1 | ALDH1A1 4411/4885LMNA 3294/4885APOBEC3A 4132/4885 |
| US-20050250744-A1 | Pharmaceutically active compounds and methods of use thereof | TREH, TET3, TUBB | ALDH1A1 4209/4885LMNA 2958/4885APOBEC3A 3675/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885LMNA 3147/4885APOBEC3A 3353/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885LMNA 3147/4885APOBEC3A 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.