Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075584 | 0.85 | KDM4E (0.48) | AMY1AKDM4EHSD17B10TUBB4ATUBB | |
| SCHEMBL28095604 | 0.85 | AMY1A (0.46) | AMY1AKDM4EHSD17B10MEN1NPC1 | |
| SCHEMBL28096010 | 0.85 | KDM4E (0.55) | GRK6KDM4EHSD17B10TUBB4ATUBB | |
| SCHEMBL28106612 | 0.83 | AMY1A (0.46) | AMY1AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL28106125 | 0.82 | NR1H2 (0.50) | AMY1AKDM4EHSD17B10MEN1NPC1 | |
| SCHEMBL28106147 | 0.82 | PSEN1 (0.47) | AMY1AKDM4EHSD17B10GAAMAPT | |
| SCHEMBL28106610 | 0.82 | NR1H2 (0.50) | AMY1AGRK6KDM4EHSD17B10NPC1 | |
| SCHEMBL28106128 | 0.82 | NPC1 (0.50) | AMY1AKDM4EHSD17B10GAANPC1 | |
| SCHEMBL28835288 | 0.81 | ADORA2A (0.47) | AMY1AMEN1NPC1MAPTRAB9A | |
| SCHEMBL28106139 | 0.81 | NPC1 (0.56) | AMY1AGRK6KDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243130-B | 3,6- diaryl-[1,2,4] triazole simultaneously [3,4-b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2019-03-01 | — | — | CN | claimed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | disclosed |