Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.51 |
| ▸ | TUBB | P07437 | 6/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.51 |
| ▸ | GRK6 | P43250 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833481 | 0.85 | AMY1A (0.46) | KDM4EPOLBTUBB4ATUBBTUBA3C | |
| SCHEMBL28095606 | 0.84 | KDM4E (0.55) | KDM4EPOLBTSHRGRK6HSD17B10 | |
| SCHEMBL28075492 | 0.84 | KDM4E (0.62) | KDM4EPOLBTSHRTUBB4ATUBB | |
| SCHEMBL17280055 | 0.83 | KDM4E (0.60) | KDM4EPOLBTSHRGRK6HSD17B10 | |
| SCHEMBL28075488 | 0.82 | KDM4E (0.58) | KDM4EPOLBTSHRTUBB4ATUBB | |
| SCHEMBL28096008 | 0.82 | KDM4E (0.55) | KDM4EPOLBTSHRGRK6HSD17B10 | |
| SCHEMBL28833548 | 0.81 | KDM4E (0.57) | KDM4EPOLBTSHRTUBB4ATUBB | |
| SCHEMBL28095619 | 0.81 | KDM4E (0.57) | KDM4EPOLBTSHRTUBB4ATUBB | |
| SCHEMBL17279690 | 0.81 | NR1H2 (0.60) | KDM4EPOLBTSHRGRK6 | |
| SCHEMBL28075564 | 0.79 | GRK6 (0.54) | KDM4EPOLBTSHRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106243130-B | 3,6- diaryl-[1,2,4] triazole simultaneously [3,4-b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2019-03-01 | — | — | CN | claimed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | claimed |
| CN-106243130-A | 3,6 diaryl [1,2,4] triazole also [3,4 b] [1,3,4] diazthines compound and application thereof | 沈阳药科大学 | 2016-12-21 | — | — | CN | disclosed |