Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768358 | 1.00 | OTC (0.38) | OTCACEFDPSMAPK11MAPK14 | |
| SCHEMBL2236439 | 0.96 | FDPS (0.39) | OTCACEFDPSALOX15KMT2A | |
| SCHEMBL28095715 | 0.96 | FDPS (0.39) | OTCACEFDPSALOX15KMT2A | |
| SCHEMBL2235726 | 0.92 | OTC (0.48) | OTCFDPSMAPK11MAPK14TDP1 | |
| SCHEMBL28102738 | 0.92 | OTC (0.48) | OTCFDPSMAPK11MAPK14TDP1 | |
| SCHEMBL28102652 | 0.88 | OTC (0.47) | OTCFDPSMAPK11MAPK14ALOX15 | |
| SCHEMBL2240203 | 0.88 | OTC (0.47) | OTCFDPSMAPK11MAPK14ALOX15 | |
| SCHEMBL1768816 | 0.86 | GFPT1 (0.37) | FDPSALOX15KMT2AADORA2AMEN1 | |
| SCHEMBL28095367 | 0.86 | GFPT1 (0.37) | FDPSALOX15KMT2AADORA2AMEN1 | |
| SCHEMBL1768781 | 0.82 | FDPS (0.41) | FDPSALOX15KMT2AMEN1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844327-B | Template-fixed peptidomimetics with CXCR7 modulatory activity | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-102712676-B | There is the peptidomimetic that the template of CCR10 antagonistic activity is fixing | 波利弗尔股份公司 | 2016-10-26 | — | — | CN | disclosed |