Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28464852 | 1.00 | MAOB (0.49) | MAOBMAPTLMNABCHEPLIN1 | |
| SCHEMBL18047059 | 0.81 | HDAC8 (0.52) | PIM1PIM3PIM2HTR6 | |
| SCHEMBL18047063 | 0.81 | HDAC8 (0.52) | PIM1PIM3PIM2HTR6 | |
| SCHEMBL18046404 | 0.80 | ADRB1 (0.49) | MAPTLMNAALDH1A1PIM1PIM3 | |
| SCHEMBL18046406 | 0.80 | ADRB1 (0.49) | MAPTLMNAALDH1A1PIM1PIM3 | |
| SCHEMBL28095918 | 0.79 | MAOB (0.76) | MAOBMAPTLMNABCHEPLIN1 | |
| SCHEMBL28095917 | 0.79 | MAOB (0.76) | MAOBMAPTLMNABCHEPLIN1 | |
| Hydrochloric Acid SCHEMBL18046347 | 0.78 | LMNA (0.50) | MAPTLMNAALDH1A1PIM1PIM3 | |
| Hydrochloric Acid SCHEMBL18046350 | 0.78 | LMNA (0.50) | MAPTLMNAALDH1A1PIM1PIM3 | |
| SCHEMBL28817356 | 0.77 | MAOB (0.62) | MAOBMAPTBCHEKDRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008400-A | New chalcone derivative, preparation method and application thereof in autoimmune diseases | 云南省中医医院 | 2016-10-12 | — | — | CN | disclosed |