Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538325 | 0.94 | NOTUM (0.41) | FEN1TSHRL3MBTL1LMNAKDM1A | |
| SCHEMBL21295047 | 0.83 | TSHR (0.49) | TSHRL3MBTL1LMNAPOLBMAPT | |
| SCHEMBL21295048 | 0.78 | FEN1 (0.36) | FEN1TSHRL3MBTL1LMNA | |
| SCHEMBL21295089 | 0.78 | FEN1 (0.36) | FEN1TSHRL3MBTL1LMNATP53 | |
| SCHEMBL21295072 | 0.77 | TSHR (0.48) | TSHRL3MBTL1LMNAPOLBMAPT | |
| SCHEMBL2330722 | 0.77 | GPR35 (0.50) | TSHRL3MBTL1LMNAKDM1ARCOR1 | |
| SCHEMBL2331226 | 0.74 | KDM1A (0.47) | TSHRL3MBTL1LMNAKDM1ARCOR1 | |
| SCHEMBL28833751 | 0.73 | L3MBTL1 (0.43) | TSHRL3MBTL1LMNAKDM1ARCOR1 | |
| SCHEMBL21295057 | 0.73 | TSHR (0.33) | FEN1TSHRL3MBTL1LMNAMAPT | |
| SCHEMBL22855746 | 0.73 | TSHR (0.36) | FEN1TSHRL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |