Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33915 | 0.84 | ELANE (0.56) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL27468878 | 0.81 | KIF11 (0.59) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL28073639 | 0.79 | CA1 (0.53) | MAPTPRSS1ACRRAB9ASMN1; SMN2 | |
| SCHEMBL6775105 | 0.79 | MAPT (0.56) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL5081953 | 0.79 | MAPT (0.49) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL1412687 | 0.78 | MAPT (0.47) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL3633529 | 0.78 | MAPT (0.64) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL6112640 | 0.77 | MAPT (0.54) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL3367629 | 0.77 | MAPT (0.58) | MAPTTDP1L3MBTL1PRSS1ACR | |
| SCHEMBL47809 | 0.77 | MAPT (0.61) | MAPTTDP1L3MBTL1PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103917094-B | Glucosylceramide Synthase Inhibitors | 建新公司 | 2016-11-09 | — | — | CN | disclosed |