Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633529 | 0.80 | MAPT (0.64) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL33915 | 0.79 | ELANE (0.56) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL11185048 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL3777454 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1TDP1HSD17B10ALOX15 | |
| SCHEMBL1790162 | 0.78 | MAPT (0.56) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL14470835 | 0.78 | EPHX2 (0.49) | MAPTALDH1A1TDP1L3MBTL1RAB9A | |
| SCHEMBL28833766 | 0.77 | MAPT (0.51) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL3367629 | 0.76 | MAPT (0.58) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL47809 | 0.75 | MAPT (0.61) | MAPTALDH1A1TDP1LMNAMAPK1 | |
| SCHEMBL21837346 | 0.75 | HDAC1 (0.53) | MAPTALDH1A1TDP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006016218-A1 | ARYL OR HETEROARYL CARBONYL DERIVATIVES DERIVATIVES USEFUL AS VANILLOID RECEPTOR 1 (VR1) ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-02-16 | — | — | WO | disclosed |