Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833984 | 1.00 | CPB1 (0.54) | CPB1CTSKCTSLCTSBMEN1 | |
| SCHEMBL19817481 | 0.88 | CPB1 (0.49) | CPB1CTSKMEN1KMT2AHSD11B1 | |
| SCHEMBL28833812 | 0.88 | CPB1 (0.49) | CPB1CTSKMEN1KMT2AHSD11B1 | |
| SCHEMBL6354112 | 0.88 | CPB1 (0.49) | CPB1CTSKMEN1KMT2AHSD11B1 | |
| SCHEMBL19814438 | 0.88 | CPB1 (0.49) | CPB1CTSKMEN1KMT2AHSD11B1 | |
| SCHEMBL19814818 | 0.88 | CPB1 (0.49) | CPB1CTSKMEN1KMT2AHSD11B1 | |
| SCHEMBL23415531 | 0.88 | CPB1 (0.54) | CPB1CTSKCTSLCTSBHSD11B1 | |
| SCHEMBL23415370 | 0.88 | CPB1 (0.54) | CPB1CTSKCTSLCTSBHSD11B1 | |
| SCHEMBL6713945 | 0.88 | CPB1 (0.53) | CPB1CTSKCTSLCTSBHSD11B1 | |
| SCHEMBL2852717 | 0.84 | CTSK (0.47) | CPB1CTSKCTSLCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |