Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28833855 | 1.00 | MAPT (0.58) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL6379443 | 0.85 | MAPT (0.59) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL6379447 | 0.85 | MAPT (0.59) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL6768435 | 0.78 | NPSR1 (0.57) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL3552839 | 0.78 | MAPT (0.76) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL7887174 | 0.78 | MAPT (0.76) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL26818738 | 0.78 | MAPT (0.76) | MAPTPKMTSHRALDH1A1MEN1 | |
| SCHEMBL6635115 | 0.77 | ALOX15 (0.43) | MAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL28833830 | 0.77 | ALOX15 (0.43) | MAPTPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL28833784 | 0.77 | ALOX15 (0.43) | MAPTPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-114901366-A | RAS inhibitors | 锐新医药公司 | 2022-08-12 | — | — | CN | disclosed |