Indole

Indole

SCHEMBL28833833

CCC=O.c1ccc2[nH]ccc2c1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
TRPA1 O75762 1/20 0.65
CA2 P00918 1/20 0.65
ITGB2 P05107 1/20 0.65
ICAM1 P05362 1/20 0.65
ITGAL P20701 1/20 0.65
AHR P35869 1/20 0.65
ADK P55263 1/20 0.65
CYP2A6 P11509 3/20 0.43
NPC1 O15118 1/20 0.39
ESR1 P03372 1/20 0.39
PARP1 P09874 1/20 0.38
CTNNB1 P35222 2/20 0.38
WNT3A P56704 2/20 0.38
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
MAOA P21397 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indole SCHEMBL28319121 0.88 AHR (0.71) CA1CA4CA6TRPA1CA2
Indole SCHEMBL345395 0.86 AHR (0.74) CA1CA4CA6TRPA1CA2
Indole SCHEMBL27922533 0.86 AHR (0.81) CA1CA4CA6TRPA1CA2
Indole SCHEMBL26612366 0.85 AHR (0.65) CA1CA4CA6TRPA1CA2
Indole SCHEMBL4865821 0.84 TRPA1 (0.55) CA1CA4CA6TRPA1CA2
Indole SCHEMBL11402854 0.84 AHR (0.77) CA1CA4CA6TRPA1CA2
Indole SCHEMBL27500374 0.82 AHR (0.68) CA1CA4CA6TRPA1CA2
Indole SCHEMBL20819817 0.82 AHR (0.74) CA1CA4CA6TRPA1CA2
Indole SCHEMBL21723436 0.82 AHR (0.74) CA1CA4CA6TRPA1CA2
Indole SCHEMBL30042337 0.82 AHR (0.74) CA1CA4CA6TRPA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105939605-A Methods for controlling weeds using formulations containing fluthiacet-methyl and hppd herbicides FMC有限公司 2016-09-14 CN disclosed