Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.51 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862940 | 1.00 | EPHX2 (0.60) | EPHX2TRPV1PTPN2PTPN1PTPN6 | |
| SCHEMBL29862953 | 1.00 | EPHX2 (0.60) | EPHX2TRPV1PTPN2PTPN1PTPN6 | |
| SCHEMBL28833970 | 1.00 | EPHX2 (0.60) | EPHX2TRPV1PTPN2PTPN1PTPN6 | |
| SCHEMBL28834223 | 1.00 | EPHX2 (0.60) | EPHX2TRPV1PTPN2PTPN1PTPN6 | |
| SCHEMBL23360626 | 0.84 | EPHX2 (0.59) | EPHX2TRPV1NPC1RAB9AKDM4E | |
| SCHEMBL23360629 | 0.84 | EPHX2 (0.59) | EPHX2TRPV1NPC1RAB9AKDM4E | |
| SCHEMBL23360653 | 0.84 | EPHX2 (0.59) | EPHX2TRPV1NPC1RAB9AKDM4E | |
| SCHEMBL29862543 | 0.84 | MET (0.56) | TRPV1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL29862978 | 0.84 | MET (0.56) | TRPV1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28834321 | 0.84 | MET (0.56) | TRPV1NPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |