Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360629 | 1.00 | EPHX2 (0.59) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL23360626 | 1.00 | EPHX2 (0.59) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28833970 | 0.84 | EPHX2 (0.60) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL29862953 | 0.84 | EPHX2 (0.60) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28833971 | 0.84 | EPHX2 (0.60) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL29862940 | 0.84 | EPHX2 (0.60) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28834223 | 0.84 | EPHX2 (0.60) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL5802659 | 0.83 | TRPV1 (0.76) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL17632155 | 0.82 | EPHX2 (0.57) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL17632153 | 0.82 | EPHX2 (0.57) | EPHX2NPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORPORATION (KR) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | EPHX2 2516/4885NPC1 2057/4885RAB9A 868/4885 |
| US-20210147386-A1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | FAP, APC, VHL | EPHX2 2516/4885NPC1 2057/4885RAB9A 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.