Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.48 |
| ▸ | TNF | P01375 | 3/20 | 0.48 |
| ▸ | LITAF | Q99732 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933364 | 1.00 | PIK3CD (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL28834114 | 1.00 | PIK3CD (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL28834238 | 0.93 | USP30 (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL29863210 | 0.93 | USP30 (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL29862661 | 0.93 | USP30 (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL28834157 | 0.93 | USP30 (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL28834155 | 0.93 | USP30 (0.49) | PIK3CDUSP30TNFLITAFPIK3CA | |
| SCHEMBL28834014 | 0.89 | USP30 (0.50) | PIK3CDUSP30BTKPARP1PIM1 | |
| SCHEMBL28834013 | 0.89 | USP30 (0.50) | PIK3CDUSP30BTKPARP1PIM1 | |
| SCHEMBL29933367 | 0.89 | USP30 (0.50) | PIK3CDUSP30BTKPARP1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |