SCHEMBL29933367

SCHEMBL29933367

Cc1cccc2c(N[C@@H]3CCN(C(=O)OC(C)(C)C)C3)ccnc12

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 9/20 0.50
PIM1 P11309 2/20 0.48
PIM2 Q9P1W9 2/20 0.48
PARP1 P09874 1/20 0.47
BRD4 O60885 1/20 0.46
BTK Q06187 2/20 0.45
CNR1 P21554 2/20 0.45
PIK3CD O00329 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28834014 1.00 USP30 (0.50) USP30PIM1PIM2PARP1BRD4
SCHEMBL28834013 1.00 USP30 (0.50) USP30PIM1PIM2PARP1BRD4
SCHEMBL23360170 0.94 ALDH1A1 (0.49) USP30PIM1PIM2PARP1BRD4
SCHEMBL29862457 0.94 ALDH1A1 (0.49) USP30PIM1PIM2PARP1BRD4
SCHEMBL29862617 0.92 USP30 (0.51) USP30PIM1PIM2PARP1BRD4
SCHEMBL28834071 0.92 USP30 (0.51) USP30PIM1PIM2PARP1BRD4
SCHEMBL28834225 0.92 USP30 (0.51) USP30PIM1PIM2PARP1BRD4
SCHEMBL29862707 0.92 USP30 (0.51) USP30PIM1PIM2PARP1BRD4
SCHEMBL28834072 0.92 USP30 (0.51) USP30PIM1PIM2PARP1BRD4
SCHEMBL28834064 0.89 USP30 (0.49) USP30PIM1PIM2PARP1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885PIM1 1984/4885PIM2 1939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.