SCHEMBL29863210

SCHEMBL29863210

COc1ccc(N[C@H]2CCN(C(=O)OC(C)(C)C)C2)c2cccnc12

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP30 Q70CQ3 5/20 0.49
PIK3CD O00329 4/20 0.49
EPHX2 P34913 1/20 0.48
PIK3CA P42336 3/20 0.47
PIK3CB P42338 2/20 0.47
PIK3CG P48736 2/20 0.47
BTK Q06187 1/20 0.46
ALDH1A1 P00352 2/20 0.46
PDE4B Q07343 1/20 0.45
USP2 O75604 1/20 0.45
GAA P10253 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TNF P01375 2/20 0.44
LITAF Q99732 2/20 0.44
CNR1 P21554 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862661 1.00 USP30 (0.49) USP30PIK3CDEPHX2PIK3CAPIK3CB
SCHEMBL28834238 1.00 USP30 (0.49) USP30PIK3CDEPHX2PIK3CAPIK3CB
SCHEMBL28834155 1.00 USP30 (0.49) USP30PIK3CDEPHX2PIK3CAPIK3CB
SCHEMBL28834157 1.00 USP30 (0.49) USP30PIK3CDEPHX2PIK3CAPIK3CB
SCHEMBL28834115 0.93 PIK3CD (0.49) USP30PIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL29933364 0.93 PIK3CD (0.49) USP30PIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL28834114 0.93 PIK3CD (0.49) USP30PIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL29862672 0.91 EPHX2 (0.51) USP30PIK3CDEPHX2PIK3CABTK
SCHEMBL28834100 0.91 EPHX2 (0.51) USP30PIK3CDEPHX2PIK3CABTK
SCHEMBL28834101 0.91 EPHX2 (0.51) USP30PIK3CDEPHX2PIK3CABTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4055014-B1 PYRROLIDINE AND PIPERIDINE COMPOUNDS YUHAN CORP (KR) 2025-04-30 EP disclosed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN disclosed
US-11655235-B2 Pyrrolidine and piperidine compounds YUHAN CORPORATION (KR) 2023-05-23 US disclosed
EP-4055014-A1 PYRROLIDINE AND PIPERIDINE COMPOUNDS Yuhan Corporation (KR) 2022-09-14 EP disclosed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655235-B2 Pyrrolidine and piperidine compounds FAP, APC, VHL USP30 1231/4885PIK3CD 641/4885EPHX2 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.