Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834297 | 1.00 | ALDH1A1 (0.54) | ALDH1A1PIK3CDNPC1MAPTMAPK1 | |
| SCHEMBL23360575 | 0.87 | GFER (0.45) | — | |
| SCHEMBL23360572 | 0.87 | GFER (0.45) | — | |
| SCHEMBL23360162 | 0.86 | ALDH1A1 (0.62) | ALDH1A1PIK3CDNPC1MAPTMAPK1 | |
| SCHEMBL28834098 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PIK3CDNPC1MAPTMAPK1 | |
| SCHEMBL28834102 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PIK3CDNPC1MAPTMAPK1 | |
| SCHEMBL28834096 | 0.82 | ALDH1A1 (0.51) | ALDH1A1PIK3CDNPC1MAPTMAPK1 | |
| SCHEMBL28834146 | 0.82 | DYRK1A (0.55) | ALDH1A1PIK3CDUSP30PIK3CAPIK3CB | |
| SCHEMBL28834148 | 0.82 | DYRK1A (0.55) | ALDH1A1PIK3CDUSP30PIK3CAPIK3CB | |
| SCHEMBL329897 | 0.81 | ALDH1A1 (0.59) | ALDH1A1PIK3CDNPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |