Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1352029 | 0.82 | RAF1 (0.48) | LCKCYP17A1CA1CA2CA12 | |
| SCHEMBL437388 | 0.82 | LCK (0.45) | LCKCYP17A1CA1CA2PI4KB | |
| SCHEMBL28834318 | 0.81 | KCNQ4 (0.41) | LCKCYP17A1CA1CA2CA12 | |
| SCHEMBL6640279 | 0.81 | CYP17A1 (0.36) | ATRLCKCYP17A1CA1CA2 | |
| SCHEMBL25360784 | 0.80 | EGLN2 (0.41) | CYP17A1CA1CA2 | |
| SCHEMBL23554099 | 0.80 | RORC (0.54) | CYP17A1HSP90AA1HSP90AB1 | |
| SCHEMBL27620314 | 0.79 | MAPT (0.43) | LCKCYP17A1CA1CA2CA12 | |
| SCHEMBL28600366 | 0.78 | RXFP1 (0.43) | CYP17A1CA1CA2METAP1 | |
| SCHEMBL438824 | 0.78 | CYP17A1 (0.35) | ATRLCKCYP17A1CA1CA2 | |
| SCHEMBL438813 | 0.77 | CYP3A4 (0.55) | ATRCYP17A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853746-A | Formamide compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-08-05 | — | — | CN | disclosed |