Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15108080 | 0.98 | KDM4E (0.48) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL9407491 | 0.87 | KDM4E (0.60) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL7770658 | 0.81 | KDM4E (0.54) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL14612175 | 0.81 | KDM4E (0.54) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL7775262 | 0.81 | KDM4E (0.54) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL1235947 | 0.80 | KDM4E (0.39) | KDM4EANPEPERAP2SMN1; SMN2EPHX1 | |
| SCHEMBL7775213 | 0.80 | KDM4E (0.62) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL7775092 | 0.80 | KDM4E (0.62) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL1043149 | 0.80 | KDM4E (0.62) | KDM4EANPEPERAP2SMN1; SMN2HTT | |
| SCHEMBL9407497 | 0.79 | KDM4E (0.52) | KDM4EANPEPERAP2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028537-B | Preparation method of aminopropyl alicyclic secondary amine | 万华化学集团股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-115028537-A | Preparation method of aminopropyl alicyclic secondary amine | 万华化学集团股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-115028537-B | Preparation method of aminopropyl alicyclic secondary amine | 万华化学集团股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115028537-A | Preparation method of aminopropyl alicyclic secondary amine | 万华化学集团股份有限公司 | 2022-09-09 | — | — | CN | disclosed |