Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331223 | 0.79 | — | — | |
| SCHEMBL879 | 0.79 | — | — | |
| SCHEMBL880 | 0.79 | — | — | |
| SCHEMBL22905077 | 0.79 | — | — | |
| Water SCHEMBL23042869 | 0.78 | LMNA (0.96) | LMNACYP2C9ALDH1A1 | |
| Water SCHEMBL23042868 | 0.78 | LMNA (0.96) | LMNACYP2C9ALDH1A1 | |
| Butyrolactone SCHEMBL29053245 | 0.70 | CA1 (0.47) | LMNAALDH1A1FKBP5 | |
| SCHEMBL28787742 | 0.69 | LMNA (0.76) | LMNACYP2C9ALDH1A1 | |
| Imidazole SCHEMBL28248513 | 0.66 | ALDH1A1 (0.54) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28866219 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106075451-A | Use SGLT2 inhibitor and combinations thereof thing that the treatment previously carried out with other antidiabetic drug is had in the patient of tolerance the method treating type ii diabetes | 阿斯利康(瑞典)有限公司 | 2016-11-09 | — | — | CN | disclosed |