Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 3/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62453 | 0.81 | CYP2C19 (0.44) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL6058614 | 0.81 | TSHR (0.36) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL28461926 | 0.71 | SMN1; SMN2 (0.44) | TSHRCYP2C19HIF1ACYP2D6ALDH1A1 | |
| SCHEMBL15554023 | 0.71 | CYP2D6 (0.39) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL4622329 | 0.70 | — | — | |
| SCHEMBL22344748 | 0.70 | CYP2C19 (0.46) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL9781854 | 0.69 | ALDH1A1 (0.46) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL3713463 | 0.69 | CYP2C19 (0.50) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL416276 | 0.69 | CYP2C19 (0.50) | HMGCRCHRM1TBXA2RADRA1ATSHR | |
| SCHEMBL4628158 | 0.69 | CYP2C19 (0.50) | HMGCRCHRM1TBXA2RADRA1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115006378-A | Medicine for preventing or treating metabolic diseases or metabolic dysfunction diseases | 西安莱格瑞生物科技有限公司 | 2022-09-06 | — | — | CN | disclosed |