SCHEMBL28835366

SCHEMBL28835366

CCC1CNCCN1S(=O)(=O)Oc1cncc(Br)c1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 5/20 0.39
CHRNA4 P43681 5/20 0.39
SMYD3 Q9H7B4 3/20 0.35
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28106928 0.70 ALDH1A1 (0.43) CHRNB2CHRNA4
SCHEMBL1605130 0.68 CHRNB2 (0.41) CHRNB2CHRNA4
SCHEMBL9267583 0.66 SMYD3 (0.36) SMYD3
SCHEMBL27864833 0.66 SMYD3 (0.36) SMYD3
SCHEMBL19002455 0.66 SMYD3 (0.36) SMYD3
SCHEMBL1606063 0.66 HTT (0.43) CHRNB2CHRNA4
SCHEMBL28702771 0.65 SMYD3 (0.38) SMYD3
Hydrochloric Acid SCHEMBL28784812 0.65 SMYD3 (0.36) SMYD3
Hydrochloric Acid SCHEMBL27770709 0.65 SMYD3 (0.36) SMYD3
SCHEMBL1605236 0.64 EPAS1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104193725-B Organic compound 诺华股份有限公司 2016-11-16 CN disclosed