Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936818 | 1.00 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMOXER1 | |
| SCHEMBL28835540 | 0.83 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL29936456 | 0.83 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL29936671 | 0.83 | OXER1 (0.48) | TSHRRAB9AL3MBTL1NOTUMOXER1 | |
| SCHEMBL28835530 | 0.82 | TSHR (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL6587897 | 0.76 | RAB9A (0.75) | TSHRRAB9AL3MBTL1NOTUMBIRC5 | |
| SCHEMBL29494636 | 0.76 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL8447109 | 0.76 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL28615748 | 0.74 | OXER1 (0.50) | TSHRRAB9AL3MBTL1OXER1MAPT | |
| SCHEMBL22956030 | 0.74 | OXER1 (0.50) | TSHRRAB9AL3MBTL1OXER1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011977-B | Method for continuously and electrically synthesizing indoline compounds by utilizing micro-reaction device | 南京工业大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-115011977-A | Method for continuously and electrically synthesizing indoline compound by using micro-reaction device | 南京工业大学 | 2022-09-06 | — | — | CN | disclosed |