Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936456 | 1.00 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL28835529 | 0.83 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL29936818 | 0.83 | TSHR (0.51) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL28835530 | 0.82 | TSHR (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL31435488 | 0.76 | RAB9A (0.75) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL9654115 | 0.72 | L3MBTL1 (0.69) | TSHRRAB9AL3MBTL1NOTUMTDP1 | |
| SCHEMBL5431558 | 0.71 | RAB9A (0.66) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL14688194 | 0.70 | TSHR (0.53) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL8447109 | 0.70 | RAB9A (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT | |
| SCHEMBL21777692 | 0.70 | TSHR (0.60) | TSHRRAB9AL3MBTL1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011977-A | Method for continuously and electrically synthesizing indoline compound by using micro-reaction device | 南京工业大学 | 2022-09-06 | — | — | CN | disclosed |