Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352393 | 0.79 | TYMP (0.54) | NOD2NOD1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL5967722 | 0.76 | MCL1 (0.49) | NOD2NOD1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL28548039 | 0.76 | POLB (0.52) | NOD2NOD1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL30343692 | 0.76 | MCL1 (0.49) | NOD2NOD1TP53KDM4ESMN1; SMN2 | |
| SCHEMBL31122079 | 0.75 | KDR (0.51) | TP53KDM4ESMN1; SMN2TSHRMCL1 | |
| SCHEMBL8360588 | 0.75 | KDR (0.51) | TP53KDM4ESMN1; SMN2TSHRMCL1 | |
| SCHEMBL14552254 | 0.74 | BRD4 (0.38) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL3972260 | 0.74 | NOD2 (0.53) | NOD2NOD1TP53KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28136871 | 0.73 | KDR (0.50) | TP53KDM4ESMN1; SMN2TSHRMCL1 | |
| Benzene SCHEMBL28136154 | 0.73 | KDR (0.50) | TP53KDM4ESMN1; SMN2TSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115011977-B | Method for continuously and electrically synthesizing indoline compounds by utilizing micro-reaction device | 南京工业大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-116217572-A | Preparation method of multi-condensed ring indoline derivative | 浙江工业大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-115011977-A | Method for continuously and electrically synthesizing indoline compound by using micro-reaction device | 南京工业大学 | 2022-09-06 | — | — | CN | disclosed |