Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Malonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.30 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL29811216 | 0.97 | LDHA (0.50) | CA4LDHASRRCASP1 | |
| Malonic Acid SCHEMBL23581218 | 0.95 | CA4 (0.45) | CA4LDHASRREGLN1 | |
| Malonic Acid SCHEMBL106382 | 0.91 | — | — | |
| Malonic Acid SCHEMBL28563570 | 0.89 | CA4 (0.45) | CA4LDHASRRCASP1 | |
| Malonic Acid SCHEMBL106340 | 0.84 | — | — | |
| Malonic Acid SCHEMBL31665936 | 0.84 | CA4 (0.60) | CA4LDHASRRCASP1LMNA | |
| Malonic Acid SCHEMBL31665937 | 0.84 | CA4 (0.60) | CA4LDHASRRCASP1LMNA | |
| Malonic Acid SCHEMBL107187 | 0.84 | — | — | |
| Malonic Acid SCHEMBL15473528 | 0.82 | CA4 (0.59) | CA4LDHASRRCASP1 | |
| Malonic Acid SCHEMBL10391172 | 0.81 | LDHA (0.60) | CA4LDHASRRCASP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989206-B | Preparation method of lithium dimalonate borate | 江苏国泰超威新材料有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-114989206-A | Preparation method of lithium dimalonate borate | 江苏国泰超威新材料有限公司 | 2022-09-02 | — | — | CN | disclosed |