Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485837 | 0.91 | BRD4 (0.50) | POLBKDM4EL3MBTL1BRD4PDE4D | |
| SCHEMBL28835658 | 0.81 | KDM4E (0.45) | POLBKDM4EL3MBTL1BRD4PDE4D | |
| SCHEMBL13935666 | 0.78 | POLB (0.46) | POLBKDM4EL3MBTL1BRD4PDE4D | |
| SCHEMBL21995909 | 0.75 | POLB (0.46) | POLBKDM4EL3MBTL1BRD4PDE4D | |
| SCHEMBL5225936 | 0.74 | HTT (0.44) | POLBKDM4EL3MBTL1PDE4DKMT2A | |
| SCHEMBL5079536 | 0.74 | HCAR2 (0.58) | POLBKDM4EBRD4PDE4DKMT2A | |
| SCHEMBL5951775 | 0.74 | KMT2A (0.58) | POLBKDM4EBRD4PDE4DKMT2A | |
| SCHEMBL7420866 | 0.74 | HCAR2 (0.50) | POLBKDM4EBRD4PDE4DKMT2A | |
| SCHEMBL1149314 | 0.73 | TSHR (0.59) | POLBKDM4EPDE4DKMT2AMEN1 | |
| SCHEMBL7421094 | 0.72 | TSHR (0.51) | POLBKDM4EBRD4PDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874143-A | Regulator containing pyrazole derivatives, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-08-09 | — | — | CN | disclosed |