Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17144656 | 0.79 | KDM1A (0.35) | KDM1AKDM1BHTR2AHTR2CSLC6A4 | |
| SCHEMBL5709356 | 0.71 | — | — | |
| SCHEMBL10935032 | 0.70 | TRPA1 (0.41) | KDM1A | |
| SCHEMBL10935029 | 0.70 | TRPA1 (0.41) | KDM1A | |
| SCHEMBL10935038 | 0.70 | TRPA1 (0.41) | KDM1A | |
| SCHEMBL12048691 | 0.68 | ESR1 (0.45) | HTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL8348272 | 0.68 | ESR1 (0.45) | HTR2AHTR2CHTR2BSLC6A4 | |
| SCHEMBL5161934 | 0.68 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA4KDM1A | |
| SCHEMBL4413078 | 0.67 | KDM1A (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4KDM1A | |
| SCHEMBL6100820 | 0.67 | PPARD (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132949-A | Substituted indone compound as the GPR119 regulator for the treatment of diabetes, obesity, dyslipidemia and associated conditions | 赛诺菲 | 2016-11-16 | — | — | CN | disclosed |