Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17721105 | 0.87 | KDM4E (0.54) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL4408676 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL16462997 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL12108945 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL13596350 | 0.82 | CYP3A4 (0.44) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL17709618 | 0.80 | MEN1 (0.56) | ALDH1A1KMT2AKDM4EMEN1MIF | |
| SCHEMBL12108929 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL14936568 | 0.79 | MEN1 (0.57) | ALDH1A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL1528350 | 0.79 | MEN1 (0.55) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL17709649 | 0.79 | ACHE (0.53) | ALDH1A1KMT2AKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096239-B | Preparation route of 9-anthrone lactone framework compound and application of analogue thereof in antitumor aspect | 中国海洋大学 | 2022-02-11 | — | — | CN | disclosed |