Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28735042 | 0.89 | CYP1A2 (0.41) | MAOAMAPTHPGDALOX15HSD17B10 | |
| SCHEMBL27741811 | 0.83 | ALDH1A1 (0.43) | MAOAMAPTHPGDALOX15HSD17B10 | |
| SCHEMBL28011796 | 0.82 | MAOA (0.48) | MAOAMAPTHPGDALOX15HSD17B10 | |
| SCHEMBL30774147 | 0.81 | IDO1 (0.52) | MAPTHPGDALOX15HSD17B10TDP1 | |
| SCHEMBL911866 | 0.81 | IDO1 (0.52) | MAPTHPGDALOX15HSD17B10TDP1 | |
| SCHEMBL18174240 | 0.80 | CYP1A2 (0.52) | MAOAMAPTHPGDALOX15HSD17B10 | |
| SCHEMBL5353432 | 0.80 | IDO1 (0.40) | MAPTHPGDALOX15HSD17B10TDP1 | |
| SCHEMBL29306847 | 0.78 | PARP1 (0.48) | ALDH1A1MAPK1CA1CA2CA7 | |
| SCHEMBL31619445 | 0.77 | IDO1 (0.48) | MAPTHPGDALOX15HSD17B10TDP1 | |
| SCHEMBL25056599 | 0.77 | MAOA (0.43) | MAOAMAPTHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114870892-B | Chiral binaphthyl catalyst and preparation method and application thereof | 上海交通大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114870892-A | Chiral binaphthyl catalyst and preparation method and application thereof | 上海交通大学 | 2022-08-09 | — | — | CN | disclosed |