Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 17/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867663 | 0.82 | HIF1A (0.81) | HIF1AHSP90AA1 | |
| SCHEMBL16867662 | 0.78 | HSP90AA1 (0.68) | HIF1AHSP90AA1 | |
| SCHEMBL16865562 | 0.75 | HIF1A (0.57) | HIF1AHSP90AA1 | |
| SCHEMBL16865563 | 0.74 | HSP90AA1 (0.66) | HIF1AHSP90AA1 | |
| SCHEMBL16694242 | 0.72 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL30749714 | 0.71 | HIF1A (0.65) | HIF1AHSP90AA1 | |
| SCHEMBL18244764 | 0.71 | HIF1A (1.00) | HIF1AHSP90AA1 | |
| SCHEMBL18244740 | 0.71 | HIF1A (0.84) | HIF1AHSP90AA1 | |
| SCHEMBL29379591 | 0.70 | HIF1AN (0.70) | — | |
| SCHEMBL28836673 | 0.70 | HIF1AN (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031592-A | Chalcone derivative, preparation thereof and application thereof in preparation of antitumor drugs or functional foods | 山东省分析测试中心 | 2022-02-11 | — | — | CN | disclosed |