Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1AN | Q9NWT6 | 12/20 | 0.70 |
| ▸ | ODC1 | P11926 | 2/20 | 0.70 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | BACE1 | P56817 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836673 | 1.00 | HIF1AN (0.70) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL16694389 | 0.85 | HIF1AN (0.87) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL16694388 | 0.85 | HIF1AN (0.87) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL31376176 | 0.85 | HIF1AN (0.87) | HIF1ANODC1ACHEPTPN1BCHE | |
| Lonchocarpin SCHEMBL29435870 | 0.84 | PTPN1 (0.83) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL29499925 | 0.83 | ODC1 (1.00) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL31376190 | 0.83 | ACHE (0.78) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL16865502 | 0.82 | ODC1 (0.84) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL19365795 | 0.81 | ODC1 (0.82) | HIF1ANODC1ACHEPTPN1BCHE | |
| SCHEMBL13534952 | 0.80 | ACHE (1.00) | HIF1ANODC1ACHEPTPN1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031592-A | Chalcone derivative, preparation thereof and application thereof in preparation of antitumor drugs or functional foods | 山东省分析测试中心 | 2022-02-11 | — | — | CN | disclosed |